Breakpoints at l l q 2 3 in Infant Leukemias With the t ( 11 ; 19 ) ( q 23 ; p 13 ) Are Clustered
نویسنده
چکیده
We have analyzed a series of nine infant leukemias that carry a t(11;19)(q23;p13). They had the morphologic features of acute lymphoblastic leukemia (ALL) and expressed markers typical of B-cell progenitor ALL or pre-6 ALL; one coexpressed myeloid markers in addition to lymphoid markers (biphenotypic). Two probes (PIS4 and 98.40) subcloned from a yeast artificial chromosome (YAC) known to span the breakpoint in the t(4;ll) were used to investigate DNA
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